We are on to the round of 32 in the NCAA Tournament after an exciting opening day (which is my personal favorite hoops day of the year). I attended the round of 64 games in Greenville, SC, so I got to see three excellent games between TCU/Ohio State, Duke/Siena, and VCU/UNC. Hopefully Friday’s games are as exciting, and I will have you covered with projections on every tournament game, both NCAA and NIT, which will be posted here at VSiN.com a day ahead of time. As always, be sure to follow me on X @TShoeIndex for all the latest tidbits and analysis, as well as women’s best bets as they come throughout the tournament as well.

Men’s Projections for 3/21

Embed from Getty Images
DateTeamTeamTSITSI Total
3/21/2026ArkansasHigh Point14.0180.2
3/21/2026DukeTCU8.6141.5
3/21/2026GonzagaTexas3.4150.8
3/21/2026HoustonTexas A&M9.3143
3/21/2026IllinoisVCU10.1161.5
3/21/2026MichiganSaint Louis8.9164.9
3/21/2026Michigan StateLouisville1.3152.4
3/21/2026NebraskaVanderbilt-0.4145.3
3/21/2026NevadaLiberty3.9148.6
3/21/2026UNC WilmingtonDayton-5.4137.8
     
Negative # = Right Team Projected Favorite
Positive # = Left Team Projected Favorite

Bets:
Michigan/Saint Louis Over 161.5
Duke/TCU Over 139.5
Dayton -2.5

Women’s Projections for 3/21

3/21AlabamaRhode Island10.1123.4
3/21ClemsonUSC-9.3127.2
3/21IllinoisColorado5.0131.3
3/21IowaFDU31.9128.7
3/21Iowa StateSyracuse4.1150.3
3/21KentuckyJames Madison13.8136.8
3/21LouisvilleVermont25.2126.5
3/21Notre DameFairfield16.0136.5
3/21Ohio StateHoward34.3134.9
3/21Oklahoma StatePrinceton11.3141.4
3/21U ConnUTSA46.2125.1
3/21UCLACalifornia Baptist45.1142.5
3/21VanderbiltHigh Point32.2149.0
3/21West VirginiaMiami (OH)21.3125.6
     
Negative # = Right Team Projected Favorite
Positive # = Left Team Projected Favorite

Bets:
Ohio State/Howard Under 142.5
Louisville/Vermont Over 121.5
James Madison +15.5

Follow me on X @TShoeIndex and add notifications to my tweets for more best bets.

The post Men’s and Women’s College Basketball Best Bets, Odds, and Predictions for Saturday, March 21 appeared first on VSiN.