Arizona Cardinals

The Arizona Cardinals rank 2nd in the NFC West for over results, posting a 39-42-4 record (48.1%) since 2020. The over has been most reliable when Arizona plays at home, where they hold a 24-16-1 mark (60.0%), and in games with a rest advantage, where they are 7-5-0 (58.3%). Conversely, the under has been strongest in road games, with a 26-14-3 record (65.0%), as well as in games with equal rest, where they are 32-26-3 (55.2%). While no sharp niche trends stand out, the straightforward home and away splits are particularly noteworthy, keeping things simple.

Los Angeles Rams

Sportsbooks and/or bettors have either overrated the Rams’ offense or underrated their defense. They hold the worst over record in the NFC West since 2020, with 40 overs, 52 unders, and 1 push (43.5% overs; 56.5% unders). The only area where overs have shown value is when the Rams are underdogs, with a 22-18-0 mark (55.0%), and more specifically as home underdogs, where they’ve gone 9-4-0 (69.2%). On the other hand, the under has been very reliable when the Rams are home favorites: 23-8-0 (74.2%), after a loss: 24-12-0 (66.7%), against AFC opponents: 16-9-0 (64.0%), and with a rest advantage: 7-4-1 (63.6%). With ongoing injury concerns around quarterback Matthew Stafford, it may be best to wait and see how he looks in the opener—if he plays at all.

San Francisco 49ers

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San Francisco holds the best over record in the NFC West since 2020, though only slightly above 50%, at 48-45-0 (51.6%). Despite the 49ers’ positive over mark, there haven’t been many strong trends, with the most consistent being games as a home underdog: 4-2-0 (66.7%), and matchups against AFC opponents: 14-11-0 (56.0%). The same goes for the under, where the clearest trends have come in games following a bye: 5-1-0 (83.3%), and contests as the underdog: 12-9-0 (57.1%). Overall, sportsbooks have been fairly sharp on San Francisco, keeping both overs and unders balanced, which makes betting their totals difficult on a week-to-week basis.

Seattle Seahawks

Similar to the Rams, Seattle Seahawks games since 2020 have leaned toward the under. Their over record in this span sits at 39-46-1 (45.9%). The only notable over trend has come when Seattle has been a home favorite, producing 16 overs, 12 unders, and 0 pushes (57.1% overs). The under, however, has been far more consistent in certain spots—specifically as a home underdog: 11-4-0 (73.3%), with a rest disadvantage: 14-8-0 (63.6%), and in divisional matchups: 19-13-0 (59.4%). With the start of a new era in Seattle under Sam Darnold, it will be worth watching whether these trends continue.