Today we wrap up the work week with a loaded 15 game MLB slate to choose from. Let’s examine where smart money is leaning for a trio of matchups using our VSiN MLB Betting Splits, which are updated every 5 minutes and come directly from DraftKings and Circa Sports.

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6:10 p.m. ET: Houston Astros at Cincinnati Reds (-130, 9)

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The Astros (15-23) just dropped two of three against the Dodgers, losing the series finale 12-2 as +180 home dogs. Meanwhile, the Reds (20-18) have lost seven straight and just got swept by the Cubs, losing 8-3 yesterday as +175 road dogs.

In tonight’s Interleague series opener, the Astros send out righty Mike Burrows (1-4, 5.97 ERA) and the Reds turn to lefty Nick Lodolo, who is making his 2026 debut after going 9-8 with a 3.33 ERA in 2025.

This line opened with Cincinnati listed as a -125 home favorite and Houston a +105 road dog.

Sharps have jumped on the Reds to end their losing streak, pushing Cincinnati up from -125 to -130.

We’ve also seen smart money back the Reds on the run-line (-1.5 at +150), as Cincinnati is receiving 67% of spread bets and 85% of spread dollars at Circa along with 55% of spread bets and 75% of spread dollars at DraftKings.

Series opening home favorites off a loss who made the playoffs the previous season, like the Reds here, are 19-9 (68%) with an 11% ROI this season.

Cincinnati has additional betting system value as an Interleague favorite, with the lack of familiarity benefiting the “better” team who is expected to win.

The Reds are 10-8 at home and 12-8 in night games. The Astros are 6-13 on the road and 7-15 in night games.

Houston is 1-6 in Burrows’ seven starts this season. He is 0-3 with a 6.23 ERA on the road.

7:10 p.m. ET: Tampa Bay Rays at Boston Red Sox (-140, 8.5)

The Rays (25-12) took last night’s series opener 8-4, coming through as +100 road dogs.

In tonight’s rematch, the Rays hand the ball to righty Jesse Scholtens (3-1, 3.18 ERA) and the Red Sox (16-22) turn to lefty Connelly Early (2-2, 3.79 ERA).

This line opened with Boston listed as a -140 home favorite and Tampa Bay a +120 road dog.

This line has either stayed the same or moved slightly in Tampa Bay’s favor (+120 to +115), signaling sneaky smart money backing the Rays at a plus money payout.

At DraftKings, Tampa Bay is taking in 55% of moneyline bets and a whopping 81% of moneyline dollars, a sharp “low bets, higher dollars” split indicating ever-so-slight public support but also heavy sharp action in the Rays’ favor.

Divisional dogs off a win, like the Rays here, are 33-31 (52%) with a 15% ROI this season.

The Rays have additional betting system value as a dog in a high total game (8.5), with the more expected runs scored leading to additional variance and upset opportunities.

Tampa Bay has the better bats, hitting .257 with a .330 OBP and 167 runs scored compared to Boston hitting .237 with a .315 OBP and 153 runs scored.

Early is 0-2 with a 6.75 ERA at home compared to 2-0 with a 2.01 ERA on the road.

The Rays are 11-8 on the road. The Red Sox are 6-11 at home.

8:05 p.m. ET: Chicago Cubs (-135, 8.5) at Texas Rangers

The Cubs (26-12) have won nine straight and just swept the Reds, winning 8-3 yesterday as -200 home favorites. On the other hand, the Rangers (17-20) have lost 7 of their last 10 and just dropped two of three against the Yankees, losing 9-2 yesterday as +130 road dogs.

In tonight’s Interleague series opener, the Cubs tap righty Ben Brown (1-1, 2.10 ERA) and the Rangers go with fellow righty Kumar Rocker (1-3, 4.71 ERA).

This line opened with Chicago listed as a -130 road favorite and Texas a +110 home dog.

Sharps have jumped on the red-hot Cubs laying short chalk, pushing Chicago up from -130 to -135 and even -140 at some shops.

At DraftKings, the Cubs are receiving 78% of moneyline bets and 83% of moneyline dollars. At Circa, Chicago is taking in 76% of moneyline bets and a whopping 98% of moneyline dollars. Both books are showing a wiseguy “low bets, higher dollars” sharp bet discrepancy in favor of the road chalk.

Chicago has additional betting system value as an Interleague favorite, with the lack of familiarity benefiting the “better” team who is expected to win.

The Cubs have the edge at the plate, hitting .258 with a .353 OBP and 208 runs scored compared to the Rangers hitting .236 with a .317 OBP and 139 runs scored.

The Cubs are 8-7 on the road and 13-4 in night games. The Rangers are 7-8 at home and 11-12 in night games.

Texas is 1-5 in Rocker’s six starts this season.

Chicago is 19-6 (76%) with a 25% ROI as a favorite, the second best chalk team in MLB.

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